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Revista médica de Chile

versão impressa ISSN 0034-9887

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QUEVEDO L, Iván; RODRIGUEZ PORTALE, José A; ROSENBERG G, Helmar  e  MERY S, Jorge. Pituitary apoplexy secondary to a metastatic renal cell carcinoma: Report of a case followed for seven years. Rev. méd. Chile [online]. 2000, vol.128, n.9, pp.1015-1018. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872000000900009.

We report a man in whom a 15 cm. renal tumor was excised at the age of 49. The pathological examination showed a clear cell carcinoma. Five years later, he presented with headache, vomiting and unilateral palpebral ptosis. Imaging studies showed a sellar tumor with pituitary apoplexy. The tumor was excised and the pathological study disclosed a clear cell tumor, positive for vimentin, cytokeratins AE1 and AE3 and immunohistochemically negative for LH, TSH, ACTH and GH. Considering the similar histopathological features, it was considered as a metastasis of the renal tumor. The patient was supplemented with thyroid, adrenal and gonadal hormones. Seven years later, he presented a new tumor in the remaining kidney, that corresponded to a cystic papillary renal cell carcinoma. Afterwards, he presented a transitional urinary bladder tumor. Mortality associated to renal cell tumors is 90% at 5 years, and pituitary metastases are extraordinarily uncommon (Rev Méd Chile 2000; 128: 1015-8).

Palavras-chave : Carcinoma, renal cell; Hypophysectomy; Pituitary apoplexy.

        · texto em Espanhol

 

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