SciELO - Scientific Electronic Library Online

 
vol.128 número12Obesidad y ácidos grasos en la etiología de la resistencia insulínicaEs hora de pensar en los derechos de los pacientes: Una introducción índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

Compartilhar


Revista médica de Chile

versão impressa ISSN 0034-9887

Resumo

SEPULVEDA C, Cecilia  e  PUENTE P, Javier. Natural Killer cells and the innate immune system in infectious diseases. Rev. méd. Chile [online]. 2000, vol.128, n.12, pp.1361-1370. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872000001200009.

Natural killer (NK) cells form a unique third group of lymphocytes that differs from T and B cells in surface phenotype, target cell recognition and function. NK cells have two relevant functions, related to the innate immune response against pathogens microorganisms. One is cytotoxicity, mediated by the recognition and lysis of target cells such as virus and bacteria infected-cells. The second NK cell function is to produce cytokines, mainly IFN-g, that can modulate innate and specific immune responses. Cytotoxicity and cytokine secretion contribute to host resistance against microorganisms and both functions are significantly altered in infectious diseases (Rev Méd Chile 2000; 128: 1361-70).

Palavras-chave : Cytokines; Killer cells; Lymphocytes.

        · texto em Espanhol

 

Creative Commons License Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons