SciELO - Scientific Electronic Library Online

 
vol.129 número2Autoanticuerpos dirigidoscontra productos de glicación avanzada en pacientes con diabetes mellitus tipo 1Alta prevalencia de enfermedad tiroidea subclínica en sujetos que concurren a control de salud índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

Compartilhar


Revista médica de Chile

versão impressa ISSN 0034-9887

Resumo

MARTINEZ-ABUNDIS, Esperanza  e  GONZALEZ-ORTIZ, Manuel. Correlation between leptin and insulin levels in mestizo-Mexican patients with preeclampsia. Rev. méd. Chile [online]. 2001, vol.129, n.2, pp.149-154. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872001000200004.

Background: Serum leptin levels increase during pregnancy and this increase is more pronounced in women with preemclapsia. Aim: To determine if there is a significant correlation of serum leptin with insulin and glucose levels in normotensive pregnant women and in preeclampsia patients. Material and methods: A nested case-control study in 16 normotensive pregnant women and in 16 preeclampsia mestizo Mexicans in the third trimester of the gestation, matched by age, gestational age and pre gestational body mass index. Venous blood samples after at least 6 h fast, were obtained and stored at -70 °C to measure serum leptin levels by ELISA, insulin concentrations by RIA and glucose by the glucose oxidase technique. Results: There were no differences between normotensive women and those with preeclampsia in serum leptin, insulin and glucose levels. There was a positive correlation between leptin and insulin concentrations (p=0.005), a negative correlation between leptin and glucose levels (p=0.02) and no correlation between leptin and pre gestational body mass index. Conclusions: In this study, women with preeclampsia did not have higher leptin levels than normotensive pregnant women (Rev Méd Chile 2001; 129: 149-54).

Palavras-chave : Insulin; Leptin; Preeclampsia; Pregnancy complications.

        · texto em Espanhol

 

Creative Commons License Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons