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Revista médica de Chile

versión impresa ISSN 0034-9887

Resumen

HUBNER G, María Eugenia; NAZER H, Julio  y  CIFUENTES O, Lucía. Ambiguous sex: prevalence at birth in a University Obstetric Wards in Santiago, Chile. Rev. méd. Chile [online]. 2001, vol.129, n.5, pp.509-514. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872001000500006.

Background: Ambiguous sex has a great phenotypic variability and is a serious medical and social problem. Aim: To study the prevalence of ambiguous sex among newborns. Material and methods: As part of the ECLAMC (Cooperative Latin American Study of Congenital Malformations) all newborns with malformations are registered and the next normal newborn is considered as a control. Results: 50.253 births occurred (between 1982 and 1999) in the University of Chile Maternity Hospital. The rate of congenital malformations was 6.78% and the prevalence of ambiguous sex was 4.7 per 10.000 births. Affected children had a lower birth weight, lower gestational age and a lower maternal age than controls. The most frequent associated malformations were of the urinary (64%) and cardiovascular systems (60.7%). Thirty two percent of affected children had specific syndromes. Conclusions: The prevalence of ambiguous sex in this study was 4.7 per 10.000 births, which is higher than that reported in the ECLAMC (1.9 per 10000). (Rev Méd Chile 2001; 129: 509-14)

Palabras clave : Abnormalities; Sex characteristics; Sex differentiation.

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