SciELO - Scientific Electronic Library Online

 
vol.129 número11Cálculo de la concentración de colesterol de la lipoproteína de baja densidad: análisis de regresión versus fórmula de FriedewaldPrevalencia de trastornos siquiátricos en hombres y mujeres hospitalizados en un Servicio de Medicina Interna de un hospital de Santiago de Chile índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

Links relacionados

Compartir


Revista médica de Chile

versión impresa ISSN 0034-9887

Resumen

SANCHEZ D, Ignacio; ALVAREZ G, Cecilia; CLAVERIA R, Cristián  y  LISBOA B, Carmen. Acoustic analysis of respiratory sounds during methacholine challenge in preschool children. Rev. méd. Chile [online]. 2001, vol.129, n.11, pp.1271-1278. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872001001100006.

Background: There are changes in inspiratory breath sound intensity in patients with airway obstruction. Airway narrowing may change sound spectral characteristics. Aim: To define the characteristics of lung sounds at standardized air flow during methacholine challenge and to compare acoustic changes with transcutaneous oxygen tension (PtcO2) during induced airway narrowing. Patients and methods: Forty asthmatic children (20 male) aged 5.2±1 years and 40 normal children (18 male), aged 5.6 ± 1 years were studied. All patients were free of respiratory tract infections one month before the study. A methacholine challenge from 0.06 to 8 mg/ml was performed; the test was ended when a fall in PtcO2 of >20% from baseline was observed or if the final concentration was reached. Subjects breathed through a pneumotachograph aiming at flows of 0.4 to 0.6 l/s. Respiratory sounds were recorded using contact sensors at the suprasternal notch and at the posterior right lower lobe. From average spectra, power at low (100-200 Hz=P1) and high frequencies (400-2000 =P2) was calculated. Frequencies below which 50% (F50) and 99% (SEF90) of the spectral power between 100 and 2000 Hz was contained, were also calculated. Results: In asthmatics, the metacholine concentration at which a 20% fall in PtcO2 was observed, was lower than in normal children (p< 0.05). There was an increase in P1 (p<0.01) and a reduction in P2 (p<0.01) during inspiration, in subjects that experienced a 20% reduction in PtcO2. Also, there was an increase in F50 and SEF99 during inspiration in lung sounds, but not over the trachea. Conclusions: Lung sounds analysis can be useful for the assessment of airway reactivity in asthmatic children (Rev Méd Chile 2001; 129: 1271-8)

Palabras clave : Asthma; Anti-asthmatic agents; Lung diseases, obstructive; Methacholine chloride.

        · texto en Español

 

Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons