SciELO - Scientific Electronic Library Online

vol.130 issue1Measured and predicted resting energy expenditure in obese and non-obese Chilean subjects: A proposal of predictive equations for the Chilean populationLength of lactational amenorrhea in an urban population of Temuco, Chile author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Revista médica de Chile

Print version ISSN 0034-9887


MORALES B, Antonio et al. An Elisa stool test to detect Helicobacter pylori infection. Rev. méd. Chile [online]. 2002, vol.130, n.1, pp.61-65. ISSN 0034-9887.

Background: Infection with Helicobacter pylori is frequent in Chile, and a good test for its diagnosis ideally should be non-invasive, fast, easy and inexpensive. Aim: To report the use of an immunoassay test, that detects antigens of Helicobacter pylori in stools. Material and methods: One hundred and four patients that required an upper gastrointestinal endoscopy were studied. Stool samples were analyzed using an enzymatic immunoassay. These results were compared with those obtained with the urease test and microscopic examination of smears taken from biopsies obtained during the diagnostic endoscopy. Results: In 81 of 83 patients considered to have the infection according to the endoscopic tests, the antigen was also present in the stools. The test was negative in 16 of 21 patients considered to be without the infection. The resulting sensitivity and specificity for the immunoassay was thus 97.6 and 76.2% respectively, with positive and negative predictive values of 92.4 and 88.9%, respectively. Conclusions: These results are in agreement with those reported in the literature. Further studies are needed to define its usefulness in massive screening, follow up after antibiotic treatments or the detection of coccoid forms of Helicobacter pylori (Rev Méd Chile 2002; 130: 61-65)

Keywords : Enzyme-linked immunosorbent assay; Helicobacter infections; Helicobacter pylori; Immunoassay.

        · text in Spanish


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License