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Revista médica de Chile

versión impresa ISSN 0034-9887

Resumen

REYES G, María Loreto; HERNANDEZ C, María Isabel; PALISSON E, Francis  y  TALESNIK G, Eduardo. Vitamin D deficiency in children with chronic diseases evaluated for osteopenia. Rev. méd. Chile [online]. 2002, vol.130, n.6, pp.645-650. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872002000600007.

Background: Chronic diseases in children may determine limited sun exposure, use of drugs, and other risk factors of osteopenia. Objective: to evaluate vitamin D deficiency and their risk factor, in children with chronic diseases with suspected osteopenia. Methods: We measured bone mineral density, bone remodeling markers, calcium, phosphate, parathormone, and 25 hydroxyvitamin D levels, and wrist X-ray. Results: We found 8 children of 25 with suspected osteopenia, with biochemical abnormalities suggestive of vitamin D deficiency. All children had low levels of 25 hydroxyvitamin D, 5 had reduced bone mineral density, 4 had hyperparathyroidism, 2 had hyperphosphatasemia, and 1 hypocalcemia and hypophosphatemia. None had rickets. Discussion: Osteopenia in chronic sick children is due to multiple factors; however, vitamin D deficiency is a preventable disorder. We recommend that all children with a chronic disease with risk factors for vitamin D deficiency should be monitored with 25 hydroxyvitamin D serum levels (Rev Méd Chile 2002; 130: 645-650)

Palabras clave : Bone diseases, metabolic; Hydroxy cholecalciferols; Osteoporosis; 25-Hydroxyvitamin D2.

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