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Revista médica de Chile

versión impresa ISSN 0034-9887

Resumen

BOEHME K, Cecilia et al. Shigella species susceptibility to commonly used antimicrobials in the Temuco Regional Hospital, Chile 1990-2001. Rev. méd. Chile [online]. 2002, vol.130, n.9, pp.1021-1026. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872002000900009.

Background: The permanent surveillance of antimicrobial susceptibility of Shigella sp in the Temuco Regional Hospital, allowed us to define the empirical use of antimicrobials in dysenteric syndrome. Aim: To study antimicrobial susceptibility of Shigella strains collected from 1997 to May 2001 and compare the results with those reported in 1990. Material and methods: Two hundred and seventeen Shigella strains, coming from stool cultures of pediatric patients, were studied. Results: In the period 1989-1990 Shigella flexneri was the main species isolated (83%) whereas, in the period 1997-2001, Shigella sonnei (55.8%) predominated. In the second period, an increase of antimicrobial resistance, as compared with the period 1989-1990, was observed for ampicillin (74.5 and 42% respectively), for cotrimoxazol (57.5 and 45% respectively) and tetracycline (64 and 8% respectively). Chloramphenicol resistance increased from 0 to 57.5%. In the second period no resistance to ciprofloxacin was detected. There was simultaneous resistance to four drugs in 30% of the strains, predominating multiresistance in S flexneri (52.1%). Conclusions: In the two periods studied, a significant increase was detected in the resistance of Shigella strains to antimicrobials (Rev Méd Chile 2002; 130: 1021-6).

Palabras clave : Antibiotics; Microbial sensitivity tests; Shigella.

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