SciELO - Scientific Electronic Library Online

vol.138 número7Colesterolosis y cáncer de la vesícula biliarAnálisis de una experiencia de consultoría ético clínica en cuidado intensivo índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados




Links relacionados


Revista médica de Chile

versión impresa ISSN 0034-9887


LUCHSINGER, VIVIAN; LUZORO, AMARANTA  y  MARTINEZ, MARÍA JOSÉ. High seroprevalence of cytomegalovirus, herpes simplex type 1 virus and Epstein Barr virus infection among human immunodefciency virus-infected adults. Rev. méd. Chile [online]. 2010, vol.138, n.7, pp.809-814. ISSN 0034-9887.

Background: Cytomegalovirus (CMV), herpes simplex type 1 (HSV-1) and Epstein Barr virus (EBV) are latent persistent infections. Their reactivation may cause illnesses and death in human immunodefciency virus-infected (HIV) people. World wide seroprevalence of these viruses is over 50%. In Chile, information is not available. Aim: To determine the seroprevalence of CMV, HSV-1 and EBV in Chilean HIV-infected adults. Patients and Methods: A total of 400 HIV- infected adults aged 17 to 67 years (340 males) were studied during 2005 and 2006. CMV, HSV-1 and EBV serum antibodies were measured by enzyme-linked immunoabsorbent assay. Results: The mean lapse from the diagnosis of HIV and serum testing was 67 months and 69.5% patients received antiretroviral therapy. Sixty seven percent of the sample were men who had sex with men (MSM). The seroprevalence for CMV, HSV-1 and EBV were 98.5, 92.2 and 99.7%, respectively. No patient had negative antibodies for all three viruses. Male patients that were negative for HSV-1 had a lower frequency of MSM than the rest of males (26% vs 62%, p < 0.01). Conclusions: There is a high prevalence of positive antibodies against CMV, HSV-1 and EBV in Chilean adults infected with HIV. Specifc diagnostic tests and antiviral therapy should be available for these patients.

Palabras clave : Cytomegalovirus; Herpesvirus 1; human; Herpesvirus 4; human; HIV.

        · texto en Español     · Español ( pdf )


Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons