SciELO - Scientific Electronic Library Online

 
vol.140 número10El cambio del perfil epidemiológico de la mortalidad materna en Chile dificultará el cumplimiento del 5° objetivo del MilenioLa presión arterial es un importante marcador de ateroesclerosis subclínica en niños índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

Links relacionados

Compartir


Revista médica de Chile

versión impresa ISSN 0034-9887

Resumen

GONZALEZ JIMENEZ, Emilio; GARCIA LOPEZ, Pedro A; SCHMIDT-RIO-VALLE, Jacqueline  y  VALENZA, Carmen. Influence of nutritional status, hormones serum levels, and family history on breast cancer development. Rev. méd. Chile [online]. 2012, vol.140, n.10, pp.1263-1267. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872012001000004.

Background: Several studies have analyzed the relation between obesity and the hormonal imbalances generated by overweight and a family history of breast cancer. All of these factors are potentially implicated in the early development of breast cancer. Aim: To verify the existence of a significant relation between the nutritional status of breast cancer patients, their hormone serum levels (estrogens, prolactin, and progesterone), and the existence of a family history of breast cancer. Material and Methods: Retrospective data was collected from clinical records of524 women diagnosed with breast cancer in a Spanish hospital. Results: There was a positive association between estrogen, progesterone and prolactin serum levels and body mass index. The elevations in hormone levels occurred earlier in life among women with a family history of breast cancer. A two way ANOVA found a significant association between progesterone and prolactin levels with the age at diagnosis of breast cancer. Conclusions: Extreme serum levels of these hormones appear to be related to the early development of breast cancer, which in turn is influenced by the existence of a family history of cancer among those women with normal or average hormone levels.

Palabras clave : Breast neoplasms; Menarche; Obesity.

        · texto en Español     · Español ( pdf )

 

Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons