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Revista médica de Chile

versão impressa ISSN 0034-9887


POLLAK C, Felipe  e  VASQUEZ A, Tatiana. Latent autoimmune diabetes in adults. Rev. méd. Chile [online]. 2012, vol.140, n.11, pp.1476-1481. ISSN 0034-9887.

Backgroud: Latent Autoimmune Diabetes in Adults (LADA) is the term used to describe adults who have a slowly progressive form of diabetes mellitus (DM) of autoimmune etiology, but that may be treated initially without insulin. Although it shares some immunological and genetic aspects with type 1 DM, it affects an age group that is typically affected by type 2 DM. Therefore, it could be considered an intermediate type. Diagnosis is based on clinical and laboratory criteria: age of onset, initial response to oral hypoglycemic agents and the presence of specific antibodies for diabetes. Although the definitive treatment is insulin, glitazones may be useful in early stages of the disease. Currently, its management represents a challenge for the physician, including specialists, and it is a form of DM to keep in mind.

Palavras-chave : Autoimmunity; Diabetes mellitus; Insulin; Thiazolidinediones.

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