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Revista médica de Chile

versão impressa ISSN 0034-9887

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AVILES-SALAS, Alejandro; CRUZ TORRES-LUCATERO, José; FERNANDEZ-SOTO, Ximena  e  CANDELARIA-HERNANDEZ, Myrna. Spindle and epithelioid hemangio-endothelioma of the lymph node: Report of one case. Rev. méd. Chile [online]. 2013, vol.141, n.2, pp.260-263. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872013000200017.

Background: Primary vascular tumors of lymph nodes are extremely rare with the exception of AlDS-related Kaposi's sarcoma. The diagnosis of epithelioid hemangio-endothelioma (EH) is difficult to make without ancillary studies, since it is devoid of morphological features indicating its vascular nature and it may be overlooked when it appears as a primary tumor of lymph nodes. Spindle and epithelioid hemangio-endothelioma (SEH) is considered to be a variant of EH, which has been reported to occur exclusively in lymph nodes and the spleen. We report a 70-year-old male with chronic lymphocytic leukemia (CLL) and left cervical lymphadenopathy. An excisional biopsy was performed, and microscopically the lymph node showed effacement of nodal architecture by a tumor composed of spindle cells disposed in intersecting fascicles, and characterized by abundant eosinophilic cytoplasm, elongated nuclei and conspicuous nucleoli. A second population of cells had an epithelioid appearance with intracyto-plasmic vacuoles containing red blood cells. lmmunohistochemically, the tumor cells were positive for CD31 and CD34. The final diagnosis was SEH of the lymph node.

Palavras-chave : Hemangio-endothelioma, epithelioid; Lymph nodes; Vascular neoplasms.

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