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vol.141 número4Pénfigo vulgar tipo cutáneo: Caso clínicoEl gran europeo Georg Friedrich Nicolai: médico y pacifista. Berlín, Alemania, 1874 - Santiago, Chile, 1964 índice de autoresíndice de assuntospesquisa de artigos
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Revista médica de Chile

versão impressa ISSN 0034-9887

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VADALA, Sabrina F et al. Lethargic Encephalitis: Report of one case. Rev. méd. Chile [online]. 2013, vol.141, n.4, pp.531-534. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872013000400016.

Lethargic encephalitis (LE) is a Central Nervous System disorder following an upper respiratory tract infection, characterized by sleep disturbances, clinical symptoms corresponding to basal ganglia involvement and in some cases, neuropsychiatric sequelae. We report a 18-year-old mole with a history of sinusitis treated with azithromycin, two weeks before, presenting with fever, headache, confusion and myoclonus. Urine analysis was positive for cannabis. Cerebro spinal fluid analysis showed mononuclear pleiocytosis (109xmm3) and an increase in protein concentration ofl.6 g/dl. Forty eight hours after admission, the patient required mechanical ventilation and subsequently a status epilepticus appeared. Ten days later, fever, rigidity and resting tremor appeared. A magnetic resonance imaging showed hyperintensities in FLALR sequence in the right insular cortex. The patient continued with extreme rigidity, catatonia and mutism. Considering the possibility ofa LE, methyl prednisolone 1 g/day was administered for five consecutive days followed by prednisone 40 mgl day, observing a dramatic improvement of rigidity and tremors.

Palavras-chave : Encephalitis; Encephalitis lethargica type Parkinsonism; Status epilepticus.

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