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Revista médica de Chile

versão impressa ISSN 0034-9887


LABARCA, Gonzalo; CRUZ N, Rodrigo  e  DESCALZI, Fernando. Multisystemic involvement in obstructive sleep apnea. Rev. méd. Chile [online]. 2014, vol.142, n.6, pp.748-757. ISSN 0034-9887.

Obstructive Sleep Apnea (OSA) is characterized by repetitive upper airway collapse with apnea/hypopnea and recurrent hypoxia during sleep, which results in fragmented sleep and intermittent drops in arterial blood oxygen saturation (hypoxemia). Several dysfunctions of neurocognitive, endocrine, cardiovascular, and metabolic systems are recognized in patients with OSA. The most commonly reported associations are with obesity, increased cardiovascular risk, dyslipidemia, diabetes mellitus 2 and liver damage. However, there is a proven relationship between OSA and other diseases, such as polycystic ovary syndrome, gastroesophageal reflux, and chronic kidney disease. The aim of this review is to analyze clinical and experimental evidence linking OSA with other diseases.

Palavras-chave : Anoxia; Hypoventilation; Respiratory insufficiency; Sleep apnea, syndromes.

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