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Revista médica de Chile

Print version ISSN 0034-9887

Abstract

PENA, Camila et al. Cerebriform variant type of T cell prolymphocytic leukemia: Report of one case. Rev. méd. Chile [online]. 2016, vol.144, n.1, pp.124-128. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872016000100016.

T cell Prolymphocytic Leukemia (T-PLL) is a rare and aggressive mature T cell Lymphocyte Leukemia. Twenty five percent of cases present as a small cell variant, and only 5% as a cerebriform variant. We report a 58 year-old man with rapidly progressive severe leukocytosis, skin lesions, lymphadenopathy, hepatosplenomegaly and pleural effusion. The lymphocytes had a cerebriform type. The diagnosis of T-PLL variant was made by morphology and immunophenotype study of peripheral blood. Karyotype was found to be complex. He was refractory to chemotherapy and died two months later.

Keywords : Immunophenotyping; Leukemia Prolymphocytic T-Cell; Leukocytosis.

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