SciELO - Scientific Electronic Library Online

vol.146 número3Encefalitis autoinmunes: criterios diagnósticos y pautas terapéuticasProblemas éticos en las publicaciones científicas índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados




Links relacionados

  • En proceso de indezaciónCitado por Google
  • No hay articulos similaresSimilares en SciELO
  • En proceso de indezaciónSimilares en Google


Revista médica de Chile

versión impresa ISSN 0034-9887


POBLETE-ARO, Carlos et al. Exercise and oxidative stress in type 2 diabetes mellitus. Rev. méd. Chile [online]. 2018, vol.146, n.3, pp.362-372. ISSN 0034-9887.

Sedentarism, overweight and malnutrition generate an increase in the production of reactive oxygen species leading to a state of chronic oxidative stress. In patients with type 2 diabetes mellitus, oxidative stress alters pancreatic insulin secretion and the actions of the hormone on target cells, contributing to the development of micro and macrovascular complications. During physical exertion a state of transient oxidative stress occurs. As a consequence, the organism generates multiple physiological adaptations to these repetitive stimuli. Physical exercise is beneficial for type 2 diabetes mellitus but there is a paucity of information about the effects of physical exercise on biomarkers of oxidative stress in patients with the disease. We herein try to elucidate if the effects of exercise on oxidative stress can help in the prevention and treatment of type 2 diabetes mellitus and which is the most effective modality of physical exercise to reduce oxidative stress markers.

Palabras clave : Antioxidant Response Element; Diabetes Mellitus, Type 2; Exercise; Oxidative Stress.

        · texto en Español     · Español ( pdf )