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Revista médica de Chile

versão impressa ISSN 0034-9887

Resumo

RODRIGUEZ-LAGOS, F. Andrea; SORLI, José V.; CALVINO-NAVEIRA, Michelle C.  e  CAPELL, Nuria Estañ. Multiple myeloma associated with a secondary amyloidosis. Report of one case. Rev. méd. Chile [online]. 2018, vol.146, n.11, pp.1351-1355. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872018001101351.

Multiple Myeloma is a myeloproliferative disorder of plasma cells, which may be complicated with secondary amyloidosis. We report a 48 year old woman consulting to primary care for weight loss and malaise. An initial laboratory study revealed a hypogammaglobulinemia with a monoclonal component and lambda light chains. These results motivated her derivation to hematology: her serum calcium was 11.8 mg/dl, immunofluorescence showed a monoclonal component of lambda chains and urine Bence-Jones protein was positive. A bone marrow biopsy confirmed plasma cell infiltration. A Congo-red stain of a rectal biopsy was positive. The patient was treated with thalidomide, bortezomid and dexamethasone.

Palavras-chave : Amyloidosis; Congo Red; Multiple Myeloma; Plasma Cells.

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