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Revista médica de Chile

versão impressa ISSN 0034-9887


SOTO, Verónica et al. Radionuclide synoviorthesis in hemophilia: experience in 107 patients. Rev. méd. Chile [online]. 2019, vol.147, n.5, pp.568-573. ISSN 0034-9887.


In patients with hemophilia, radionuclide synoviorthesis, or the intra-articular injection of a radionuclide to decrease the synovial hypertrophy tissue, aims to decrease or avoid hemarthrosis.


To evaluate the effectiveness of radionuclide synoviorthesis in hemophilia.

Material and Methods:

Observational retrospective study of the evolution of 107 male patients aged 3 to 54 years who were subjected to radionuclide synoviorthesis between 2007 and 2015.


Of 164 treated joints, in 65% treatment was successful, (defined as zero to two hemarthroses and absence of synovitis during the follow up period), in 17% it was partially successful (defined as two or less hemarthroses, but persistence of the synovitis) and failed in 18% of the procedures. No important complications were recorded.


Radionuclide synoviorthesis has an overall 82% success rate, is minimally invasive, can be used at any age and is inexpensive We recommend its implementation in Chilean hemophilia treatment centers.

Palavras-chave : Hemarthrosis; Hemophilia; Synovitis.

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