SciELO - Scientific Electronic Library Online

 
vol.147 número7Anemia hemolítica autoinmune en Chile: un análisis retrospectivo de 43 pacientesCaracterización de tumores secretores de hormona de crecimiento de acuerdo al patrón granular y su rol en el pronóstico índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

Links relacionados

  • En proceso de indezaciónCitado por Google
  • No hay articulos similaresSimilares en SciELO
  • En proceso de indezaciónSimilares en Google

Compartir


Revista médica de Chile

versión impresa ISSN 0034-9887

Resumen

FICA, Alberto et al. Host characteristics predict outcome among adult patients admitted by severe acute respiratory infection. Rev. méd. Chile [online]. 2019, vol.147, n.7, pp.842-851. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872019000700842.

Background:

Except for influenza pandemics, different observational studies have failed to demonstrate differences in mortality between various etiologies in adult patients hospitalized for respiratory infections.

Aim:

To compare clinical and mortality differences between different viral pathogens associated with severe acute respiratory infections (SARI) in hospitalized adults.

Material and Methods:

One-year prospective study in a sentinel center. We included 132 patients with SARI hospitalized for any of the nine viruses under study by PCR. Clinical variables were compared, excluding cases of coinfection.

Results:

A viral coinfection was identified in 12% and influenza infection in 56% of cases. Eighty percent of patients were aged ≥ 65 years, with a high frequency of comorbidities, 27% were bedridden. Twenty four percent were admitted to critical care units, 20% required ventilatory assistance and 16% died. Cases occurred throughout the year, with an expected seasonal peak between autumn and spring and a predominance of infections not associated with influenza during summer months. In the multivariate analysis, only being bedridden was significantly associated with mortality at discharge (Odds ratio 23.46; 95% confidence intervals 3.33-165.12, p < 0.01), without association with age, comorbidity, viral pathogen involved, laboratory parameters, clinical presentation or CURB65 score. No major clinical dissimilarities were found between different viral pathogens.

Conclusions:

In our series of patients, mostly elderly, only bedridden status was significantly associated with mortality at discharge in patients hospitalized for SARI. Viral pathogens were not relevant.

Palabras clave : Bedridden Persons; Frail Elderly; Mortality; Respiratory Tract Infections; Virus Diseases.

        · resumen en Español     · texto en Inglés     · Inglés ( pdf )