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Revista médica de Chile

versão impressa ISSN 0034-9887

Resumo

ROCO, Ángela et al. Comparison of point of care capillary international normalized ratio (INR) with INR measured in venous samples. Rev. méd. Chile [online]. 2019, vol.147, n.10, pp.1273-1282. ISSN 0034-9887.  http://dx.doi.org/10.4067/s0034-98872019001001273.

Background:

INR is used to monitor the treatment with vitamin K antagonists. A strategy to reduce waiting times for sampling is to measure INR in a capillary sample using a portable point of care (POC) type coagulometer.

Aim:

To evaluate the correlation of CoaguChek Pro II™, Xprecia™ and microINR™ with venous INR measured at the clinical laboratory and their ease of use.

Materials and Methods:

Patients provided capillary and venous blood samples for parallel tests comparing Xprecia™ Stride with CoaguChek Pro II™ and with venous INR, microINR™ with CoaguChek Pro IITM and with venous INR. The devices’ ease of use was assessed surveying the sampling staff.

Results:

The three tested devices had good correlation coefficients with venous INR: CoaguChek Pro IITM 0.953 and 0.962; Xprecia™ of 0.912 and microINR™ of 0.932. The correlation coefficient of Xprecia™ with CoaguChek Pro IITM was 0.937 and microINR™ with CoaguChek Pro IITM was 0.976.

Conclusions:

CoaguChek Pro IITM, Xprecia™ and microINR™ results had a good correlation coefficient with INR measured at the laboratory. Our results indicate that, in the hands of trained users, POC-type coagulometers are reliable and acceptable for routine use in anticoagulant treatment control.

Palavras-chave : Acenocoumarol; Anticoagulants; International Normalized Ratio.

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