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Revista médica de Chile

versión impresa ISSN 0034-9887

Resumen

MERELLO, LORENZO et al. Hospital mortality and long-term survival of 103 patients with infective endocarditis requiring surgery. Rev. méd. Chile [online]. 2019, vol.147, n.12, pp.1535-1542. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872019001201535.

Background

Infective endocarditis (IE) is a serious disease with high mortality, especially among the most severe cases undergoing surgery.

Aim

To analyze the clinical features, perioperative mortality and long-term survival of patients with infective endocarditis requiring surgery.

Material and Methods

Review of medical records of patients who underwent heart valve surgery for active infective endocarditis in a public hospital between 1995 and 2008. Demographic characteristics and comorbidities were described. Perioperative and 10 year survival were analyzed retrieving death certificates from the Chilean Identification Service.

Results

Data from 103 patients aged 46 ± 14 years (74% males) was analyzed. Thirty five percent of patients had an underlying predisposing heart condition such as congenital heart disease in 18.5% and prosthetic valves in 10%. The most common location was the aortic valve and the most common surgical procedure was heart valve replacement with a mechanical prosthetic valve in 87% of the cases. Pathogen identification in blood cultures was achieved in 48% of the cases. The most common causative microorganisms were S. aureus in 12%, coagulase-negative Staphylococcus in 11%, S. viridans in 10% and Enterococcus in 7%. Hospital mortality was 20.4% and ten-year survival was 65%.

Conclusions

Patients with severe IE requiring surgical treatment still have high perioperative and late mortality.

Palabras clave : Endocarditis, Bacterial; Heart Value Prosthesis Implantation; Survival Analysis.

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