SciELO - Scientific Electronic Library Online

vol.147 número12Hierro intravenoso en la terapia del síndrome de piernas inquietasEstudio imagenológico del síndrome aórtico agudo índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados




Links relacionados

  • Em processo de indexaçãoCitado por Google
  • Não possue artigos similaresSimilares em SciELO
  • Em processo de indexaçãoSimilares em Google


Revista médica de Chile

versão impressa ISSN 0034-9887


A. SEPULVEDA, RODRIGO et al. Intoxicación por etilenglicol, fisiopatología y enfrentamiento clínicoEthylene glycol poisoning. An update. Rev. méd. Chile [online]. 2019, vol.147, n.12, pp.1572-1578. ISSN 0034-9887.

Toxic alcohols can produce severe poisoning with multiple organic involvement and even death. The most common form is ethylene glycol. The diagnosis can be extremely difficult if there is no history of its consumption. Its clinical presentation can simulate other conditions. Ethylene glycol poisoning is characterized by an initial rise in plasma osmolal gap that decreases during the evolution, while alcohol is metabolized to acids. This last condition causes a metabolic acidosis with elevated anion gap. The clinical manifestations are diffuse neurological involvement initially, followed by hemodynamic alterations due to myocardial damage associated with hypocalcemia and acidemia. Subsequently, severe tubular renal damage appears, which may require renal replacement therapy, and finally, focal neurological alterations. To treat this poisoning, it is necessary to inhibit the transformation of alcohol into acids, increase the metabolism of the latter or withdraw them directly with hemodialysis.

Palavras-chave : Alcohols; Ethylene Glycol; Poisoning; Therapeutics.

        · texto em Inglês     · Inglês ( pdf )