Resumen

CROSSLEY, R; COLOMA, A; RIOS, C  y  GONZALEZ, C. Determination of C-reactive protein in female dogs with benign and malignant mammary tumors. Arch. med. vet. [online]. 2010, vol.42, n.1, pp.101-105. ISSN 0301-732X.  http://dx.doi.org/10.4067/S0301-732X2010000100014.

The aim of this study was to determine C-reactive protein levels in dogs with benign and malignant mammary tumors. Thirty female dogs, with ages ranging between 6 and 15 years and with no distinction of breed were used for this purpose. The animals were divided into 3 different groups of 10 dogs each: Group 1 (control), Group 2 (benign mammary tumor) and Group 3 (malignant mammary tumor). The neoplasias were classified histologically and C-reactive protein (CRP) levels were analyzed using a human turbidimetric immunoassay validated for dogs. Group 3 had the highest values (mean: 8.2 mg/L; median: 7.1 mg/L) of C-reactive protein compared with the other groups (P < 0.05). According to a discriminant analysis, a female dog with a mammary tumor and CRP values ≥ 8 mg/L has a 61% or greater probability of this tumor being malignant.

Palabras clave : C-reactive protein; mammary tumors; malignant.

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