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vol.45 issue4CARACTERIZACION Y SEPARACION DE UNA ESTILBITA ORIGINARIA DE LA REGION DE ATACAMA, CHILENEUTRAL COMPLEXES OF SILVER HALIDES AND TETRAMETHYLTHIURAM MONOSULFIDE author indexsubject indexarticles search
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Boletín de la Sociedad Chilena de Química

Print version ISSN 0366-1644

Abstract

ASTUDILLO S., LUIS et al. BIOLOGICALLY ACTIVE COMPOUNDS FROM CHILEAN PROPOLIS. Bol. Soc. Chil. Quím. [online]. 2000, vol.45, n.4, pp.577-581. ISSN 0366-1644.  http://dx.doi.org/10.4067/S0366-16442000000400008.

A propolis sample from the western Andean slopes of the Maule Region, Chile, showed free radical scavenging activity and inhibited the enzyme xanthine oxidase "in vitro". Six flavonoids were isolated as the main active constituents of the sample. 5,7-dihydroxyflavone 4, 3,5,7-trihydroxyflavone 6 and 5,7-dihydroxyflavanone 1 displayed a strong free radical scavenging effect. At 50 mg/ml, compounds 6 and 1 inhibited the enzyme xanthine oxidase by 95 and 86%, respectively.

Keywords : propolis; flavonoids; free radical scavenging activity; DPPH.

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