SciELO - Scientific Electronic Library Online

 
vol.46 issue3CONFORMATIONAL DYNAMICS OF SUBSTITUTED N-ACETYL-N-PHENYLBENZYLAMINES. 1H-DNMR AND AM1-MO STUDYOPTIMIZACION DE UNA TECNICA DE MUESTREO IN SITU: ANÁLISIS DE Cu Y Fe EN SISTEMAS ACUÁTICOS author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

Share


Boletín de la Sociedad Chilena de Química

Print version ISSN 0366-1644

Abstract

KESTERNICH, VICTOR; CONTRERAS-ORTEGA, CARLOS  and  MARTINEZ, ROLANDO. A THEORETICAL STUDY OF THE STEREOCHEMICAL COURSE OF THE ACID CYCLIZATION OF TWO 5-OXOGERMACREN- 6,12-OLIDES EPIMERIC IN C4. Bol. Soc. Chil. Quím. [online]. 2001, vol.46, n.3, pp.271-279. ISSN 0366-1644.  http://dx.doi.org/10.4067/S0366-16442001000300006.

The theoretical study of both the conformational distribution and the acid cyclization of two epimeric 5-oxogermacren-6,12-olides in C4 is described. Our results on the stereochemistry of the cyclization products, 5-hydroxyguaian-6,12-olides, agree with experimental results reported previously. Curtin-Hammet principle and Hammond postulate are used to propose reaction pathways consistent with above results. The theoretical results were obtained by using a MM2 program from HyperChem 4.5

Keywords : Sesquiterpenic lactones; germacranolides; guaianolides; MM2 program.

        · abstract in Spanish     · text in English

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License