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Revista chilena de pediatría

versión impresa ISSN 0370-4106

Resumen

MARTINEZ A, Juan Carlos; GONZALEZ L, Claudia  y  SOTOMAYOR F, Cristián. Type III bipolar disorder in children: an infrequent diagnosis. Rev. chil. pediatr. [online]. 2004, vol.75, n.5, pp.420-424. ISSN 0370-4106.  http://dx.doi.org/10.4067/S0370-41062004000500002.

Introduction: Antidepressants have been associated with the induction of hypomania and mania. Objective: to actualise the concept of pharmacological switch to hypomania and its relevance in bipolar type III depression. Methodology: Medline search using the key words antidepressives, pharmacological switch, type III bipolarity. Results: The antidepressant associated mania occurs more frequently in bipolar depression, the use of tricyclic antidepressants and the duration of treatment. Conclusions: Unipolar patients who switch to a bipolar illness with the use of antidepressants, and who have not developed a bipolar phase spontaneously before are called pseudo-unipolar and are classified within the spectrum of type III bipolar disorder. Pharmalogical switch is the best predictor for the development of bipolar illness with a 100% specificity

Palabras clave : antidepressants; pharmacological switch; type III bipolar disorder.

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