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Revista chilena de pediatría

versão impressa ISSN 0370-4106

Resumo

CUBAS R, CESAR et al. Severe respiratory distress associated to Metapneumovirus infection in infants. Rev. chil. pediatr. [online]. 2007, vol.78, n.2, pp.165-168. ISSN 0370-4106.  http://dx.doi.org/10.4067/S0370-41062007000200007.

Background: In 2001, dutch researchers reported a new virus able to cause high and low acute respiratory infection (ARI) in children. It belongs to the Paramyxoviridae family and constitutes the first human pathogen in the genus Metapneumovirus: human Metapneumovirus (hMPV). Objective: Report a retrospective review of 4 infants with hMPV low ARI with severe respiratory failure, admitted in Pediatric Intensive Care Unit between November 2005 and September 2006 and review the literature. Patients and Methods: Common respiratory virus and Bordetella pertussis were ruled out. Polymerase chain reaction was performed to detect the fusion protein(f)of hMPV and Adenovirus cellular culture. Results: All 4 cases had obstructive bronchial syndrome (OBS), 3 required invasive mechanical ventilation and 2 cases presented spontaneous pneumotorax. Co-infection with Adenovirus was detected in 2 cases. Bacterial cultures were negative. No patients died. Conclusion: hMPV must be suspected in infants with severe acute respiratory failure. The co-infection with Adenovirus must be ruled out

Palavras-chave : Metapneumovirus; infant; acute respiratory infection.

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