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Revista chilena de pediatría

versión impresa ISSN 0370-4106


DONOSO F, ALEJANDRO; ARRIAGADA S, DANIELA; CRUCES R, PABLO  y  DIAZ R, FRANCO. Septic shock in pediatrics I: Current approach in diagnosis and therapeutics. Rev. chil. pediatr. [online]. 2013, vol.84, n.5, pp.484-498. ISSN 0370-4106.

Septic shock is a major cause of infant mortality worldwide and represents the progressive underlying inflammatory pathway secondary to an infectious disease, which causes acute cardiovascular dysfunction, not necessarily hypotension, tissue dysoxia and eventually cellular and organ failure. Standard resuscitative measures emphasize clinical recognition and early treatment. These interventions are based on early and aggressive resuscitation with intravenous fluids to optimize tissue perfusion, antibiotics, removal of the source of infection and the use of vasoactive drugs if necessary. Therapy should be permanently evaluated according to the standardized laboratory and clinical targets. This publication is an update on the epidemiology and pathophysiology of sepsis, operational definitions, current international campaigns and initiatives concerning proposals to decrease the morbidity and mortality of this condition. It also addresses initial therapeutic approaches in the emergency room. The aim of this study is to present the current state of knowledge in the diagnosis and treatment of patients with septic shock especially in the initial phase before admissions to intensive care units.

Palabras clave : Sepsis; septic shock; bacteremia; resuscitation; pediatric emergency.

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