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Revista chilena de pediatría

Print version ISSN 0370-4106

Abstract

CORVALAN, Alejandro H  and  MATURANA, María José. Infections and epigenetic changes in cancer. Rev. chil. pediatr. [online]. 2016, vol.87, n.4, pp.245-249. ISSN 0370-4106.  http://dx.doi.org/10.1016/j.rchipe.2016.06.008.

The role of epigenetics and infectious diseases at early stages of life influence pre-malignant lesions of cancer, in particular, gastric cancer, one of the most frequent tumours in Chile, Latin America, and worldwide. This article examines the role of H.pylori and epigenetic alterations (i.e. DNA methylation) at early stages of gastric cancer and proposes, from the paediatric point of view, strategies for prevention and early detection.

Keywords : Helicobacter pylori; DNA methylation; Gastric cancer.

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