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Revista chilena de pediatría

versión impresa ISSN 0370-4106


SCHILLING, Karin W.; YOHANNESSEN, Karla  y  ARAYA, Magdalena. Perception of following gluten-free diet and adherence to treatment in pediatric patients with celiac disease. Rev. chil. pediatr. [online]. 2018, vol.89, n.2, pp.216-223.  Epub 04-Abr-2018. ISSN 0370-4106.


Celiac disease (CD) is a chronic immune-mediated enteropathy present in ~1% of population. Gluten-free diet (GFD) is the only treatment for this condition and the main limitation of its efficacy is the lack of adherence.


To assess factors influencing adherence to GFD in pediatric patients and measure the concordance between serological results and a nutritional adhe rence questionnaire.

Patients and Methods:

celiac patients younger than 18 years of age, diagnosed CD following ESPGHAN criteria, on GFD for at least 6 months and consulting at Hospital Roberto del Río, Santiago, in 2008-2016, were assessed. Clinical presentation, nutritional evaluation and fac tors related to adherence to treatment (diet) were registered. A subsample answered Biaggi's nutri tional questionnaire.


Of 65 evaluated patients, 44% and 30,1% adhered to GFD according to blood autoantibodies (TTG and EMA) and the adherence questionnaire, respectively. “Age at debut” (p = 0.049), “perception of following GFD correctly” (p = 0.002) and “behavior in social events” (p = 0.005) were significantly associated with adherence to GFD. There was concordance between serological test and Biagi’s questionnaire (p = 0.0001).


Adherence to GFD was lower than reported in literature. Intervention of some of the identified variables associated with adherence may help improving follow-up of celiac patients, especially those that due to diverse situations cannot measure their antibodies periodically.

Palabras clave : Celiac disease; gluten; adherence; perception; ESPGHAN.

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