SciELO - Scientific Electronic Library Online

vol.90 issue2Dysregulation profile defined by Child Behavior Checklist in a sample of preschool childrenDevelopment of communicative abilities in infants with Down syndrome after systematized training in gestural communication author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


Revista chilena de pediatría

Print version ISSN 0370-4106


MATUS C., Patricia  and  OYARZUN G., Manuel. Impact of Particulate Matter (PM 2,5 ) and children’s hospitalizations for respiratory diseases. A case cross-over study. Rev. chil. pediatr. [online]. 2019, vol.90, n.2, pp.166-174. ISSN 0370-4106.


With seven million inhabitants, Santiago de Chile reaches high levels of air pollution in winter, the particulate matter usually exceeds WHO standards.


To assess the influence of air pollution caused by particulate matter on children’s hospitalizations due to respiratory diseases between 2001 and 2005 in the Metropolitan Region of Chile, independently from the environmental presence of respiratory syncytial virus (RSV).

Material and Method:

72,479 public and private hospitalizations due to respiratory diseases of children under 15 years of age residing in the study region were analyzed using a time-stratified alternating case-control design. The main evaluations were: hospitalizations due to respiratory diseases (J00-J99), pneumonia (J12-J18); asthma (J21.0 - J21.9), and bronchiolitis (J45 - J46). Daily compilation of temperature data, PM10, PM2,5, ozone, respiratory virus (RSV), and environmental humidity.


Mean values of PM10 and PM2.5 were 81.5 and 41.2 pg/m3 respec tively. The average temperature was 12.8 °C and air humidity 72.6%. An increase of 10 pg/m3 of PM25 with one and two days of lag was associated with an hospitalizations increase due to respiratory diseases close to 2%, this percentage increased to 5% when the exposure was with eight days of lag, reflecting synergism between particulate matter and respiratory viruses (RSV).


Short air pollution exposure can lead to children’s hospitalizations due to respiratory diseases.

Keywords : Air Pollution; Hospitalization; Child; Pneumonia; Bronchiolitis; Asthma; Respiratory Syncytial Virus; Alternate Case-Control Studies.

        · abstract in Spanish     · text in English | Spanish     · English ( pdf ) | Spanish ( pdf )