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Revista chilena de infectología

versión impresa ISSN 0716-1018

Resumen

FICA C., ALBERTO. INFLUENZA: PROPHYLAXIS THROUGH ACTIVE IMMUNIZATION. Rev. chil. infectol. [online]. 2001, vol.18, n.2, pp.133-141. ISSN 0716-1018.  http://dx.doi.org/10.4067/S0716-10182001000200007.

The available medical alternatives for confronting influenza virus infection have been optimized by the development of more secure and well tolerated vaccines than the original immunization alternatives. The efficacy of active immunization against influenza has been demostrated in various clinical trials that support its benefit in immunized people with rates of efficacy over 70% in general population and at least 50% in patients over 65 years of age. The parenteral formulas constitute now the principal alternative in the market (as whole virus, split vaccine or purified antigens) and can be administered universally, including immunosuppressed patients, because it contains inactivated virus. The attenuated virus vaccines are under development, they are not available yet and they could be contraindicated in some immunosuppresed patients. Its advantage lies in the administration by nasal route that would facilitate its adherence during immunization campaigns

Palabras clave : Influenza; Immunoprophylaxis; Vaccines.

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