SciELO - Scientific Electronic Library Online

vol.24 issue6Tuberculosis and AIDS in Pediatrics: on account of five casesAdherence to immunization among children with special health care needs author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Revista chilena de infectología

Print version ISSN 0716-1018


PENA D, Anamaría et al. Cytomegalovinas disease in HIV-1 infected Chilean children. Rev. chil. infectol. [online]. 2007, vol.24, n.6, pp.477-484. ISSN 0716-1018.

Cytomegalovirus (CMV) is a frequent opportunistic infection in human inmunodeficiency virus type 1 (HIV-1) infected children associated with significant morbidity and mortality. The aim of this study was to determine the frequency and impact of CMV disease in a prospective ly followed cohort of HIV-1 infected Chilean children. CMV disease was diagnosed in 28 out of 222 HIV infected children (12.6%); 92% of them were classified in category C and 61% in category 3 (CDC, 1994). Lung disease was the most common manifestation (25 children). Samples were obtained from the respiratory tract, blood, urine and tissue biopsies. Shell vial for CMV early antigen detection was the most commonly used diagnostic technique (20/ 28). All patients were treated with iv.ganciclovir and two children died during the CMV episode. The mean survival time for the remaining children is currently 42 months. Conclusion: CMV disease was frequent and caused mortality in HIV-1 infected Chilean children. Early diagnosis and treatment are key for clinical success

Keywords : cytomegalovirus; human immunodeficiency virus type 1; children.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License