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Revista chilena de infectología

versão impressa ISSN 0716-1018

Resumo

TOBAR A, Eduardo et al. Invasive candidiasis in critically ill adult patient. Rev. chil. infectol. [online]. 2011, vol.28, n.1, pp.41-49. ISSN 0716-1018.  http://dx.doi.org/10.4067/S0716-10182011000100008.

Invasive infections by Candida strains are a relevant pathology in critically ill patients. Candida should be considered where a high risk of infection is present for a critical early diagnosis. Despite the incorporation of new drugs in the therapeutic armamentarium over the last decade, mortality remains high. The key in improving clinical outcomes of these patients are the use of early effective therapies that offer coverage against different strains of Candida: C. albicans and non-albicans. Recent international guidelines suggest empiric therapy with echinocandins in suspected invasive candidiasis in this patient population. This group of drugs adequately documented clinical efficacy and safe use in these patients. The emergence of new echinocandins could improve access to these drugs by reducing their cost.

Palavras-chave : Mycoses Candida spp; fungal infection; critical illnesses; echinocandins.

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