SciELO - Scientific Electronic Library Online

vol.28 issue2Comparison of real-time polymerase chain reaction and antigenemia assay to detect cytomegalovirus in pediatric transplantsInvasive fungal disease in patients from five hospitals in the Valparaíso Region, Chile: 2004 to 2009 author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Revista chilena de infectología

Print version ISSN 0716-1018


AJENJO H, M. Cristina et al. Epidemiologial profile of invasive candidiasis in intensive care units at a university hospital. Rev. chil. infectol. [online]. 2011, vol.28, n.2, pp.118-122. ISSN 0716-1018.

Invasive candidiasis (IC) epidemiology has changed in critically ill patients and limited data are available in Chile. Objective: To describe the epidemiological and microbiological profile of IC in critically ill patients. Methods: Observational prospective study conducted from October 2001 to August 2003 in critically ill adults with suspected or confirmed IC. Results: 53 patients met criteria for IC, finding 18 (33.9%) candidemias, 22 (41.5%) disseminated IC, and 13 (24.5%) local IC. We identified 8 (44.4%) C. albicans and 10 (55.6%) non-albicans Candida in candidemias. C. tropicalis was the predominant non-albicans species (27.7%). An 88.8 % of Candidas sp recovered in candidemias were fluconazole susceptible. Overall hospital mortality was 24.5%. Mortality in candidemia was significantly lower than in disseminated IC (16.6 vs 31.8%, p = 0.02). Conclusions: A higher proportion of non-albicans Candida was observed in candidemias from critically ill patients. However, most of these strains were fluconazole susceptible. A lower overall mortality was observed in candidemias.

Keywords : Invasive candidiasis; intensive care unit fluconazole.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License