Resumen

BONACIC, Macarena; SILVA, Alfredo  y  WOLFF, Marcelo. Failure of cotrimoxazole prophylaxis for Pneumocystis jiroveci pneumonia with concomitant use of leucovorin: Case report. Rev. chil. infectol. [online]. 2012, vol.29, n.5, pp.572-572. ISSN 0716-1018.  http://dx.doi.org/10.4067/S0716-10182012000600020.

The concomitant use of leucovorin and cotrimoxazole in PCP can lead to therapeutic failure and increased risk of death due to antagonism. It is important to keep this possible antagonistic interaction in mind even during prophylaxis. This paper presents a case with this failure outcome.

Palabras clave : eucovorin; folinic acid; Pneumocystis jiroveci; HIV prophylaxis; trimethoprim-sulfamethoxazole.

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