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Revista chilena de infectología

versión impresa ISSN 0716-1018

Resumen

VLLLARROEL, Julia et al. Incidence of cáncer in Chilean HIV-infected children. Rev. chil. infectol. [online]. 2015, vol.32, n.6, pp.672-676. ISSN 0716-1018.  http://dx.doi.org/10.4067/S0716-10182015000700009.

Background: Pediatric HIV (+) patients have a 100 times greater risk of cancer than HIV (-) children. Objective: To describe in Chilean HIV (+) children, cancer types, its appearance in relation to the stages of HIV disease and mortality. Methods: A protocol was created to know some characteristics of these patients from the point of view of their HIV infection and cancer pathology. Results: Of 360 HIV (+) children confirmed by the Institute of Public Health to May 2014, 9 patients with neoplastic disease (2.5%) were diagnosed. All the children were on ART, had more than three years of evolution of HIV infection and were in moderate to severe clinical/immunological stages. Lymphoma was the most common cancer. Five children, has received therapy according to Programa Infantil Nacional de Drogas Antineoplásicas (PINDA). There was no interaction between cancer treatment and antiretroviral therapy. Mortality was 13.8 x 1000 (5 cases). Conclusions: The incidence and type of neoplasia is consistent with the international literature, with less survival than HIV (+) children without tumors. The occurrence of cancer was observed in children with moderate to severe clinical and immunological compromise.

Palabras clave : Malignancies; HIV; non-Hodgkin's lymphoma.

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