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Revista chilena de infectología

versión impresa ISSN 0716-1018

Resumen

DE LA ROSA, Gisela; LEON, Alba Luz  y  JAIMES, Fabián. Epidemiology and prognosis of patients with bloodstream infection in 10 hospitals in Colombia. Rev. chil. infectol. [online]. 2016, vol.33, n.2, pp.141-149. ISSN 0716-1018.  http://dx.doi.org/10.4067/S0716-10182016000200003.

Background: Knowing the local epidemiology and etiology of bloodstream infections allows tailoring the empirical initial antimicrobial therapy to obtain a better outcome for these episodes. Aim: To describe the epidemiological and microbiological aspects as well as the factors associated with mortality in patients with bloodstream infection in Colombian hospitals. Methods: Sub-analysis of a prospective cohort study of 375 consecutive patients with bloodstream infection in 10 hospitals in Colombia, admitted between September first 2007 and Febrnary 29, 2008. Results: The most frequently isolated bacteria were Gram-negative bacilli in 54% of patients, followed by Gram-positive cocci in 38.4%. The source of infection was known in 67%, unknown in 24% and associated with intravascular catheter in 9%. The most frequently isolated bacteria were Escherichia coli (46%), coagulase-negative Staphylococci (16%), Klebsiella pneumoniae (8.9%) and Staphylococcus aureus (7.8%). Staphylococcus aureus was methicillin sensitive in 82% of patients (46/56). Overall 28-day mortality was 25% and their independent associated factors were age, SOFA score and APACHE II score. Conclusions: In our study the most frequently isolated bacteria in bloodstream infections were Gram-negative bacilli, contrasting those reported in developed countries. The overall mortality rate was high and the factors associated with mortality were age and severity scores.

Palabras clave : Bloodstream infection; bacteremia; bacteremia associated mortality; community-acquired bacteremia; nosocomial bacteremia.

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