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Revista chilena de infectología

versión impresa ISSN 0716-1018

Resumen

PERRET, Cecilia et al. Chikungunya, emerging disease in Latin America. Description of the first cases in Chile. Rev. chil. infectol. [online]. 2018, vol.35, n.4, pp.413-419. ISSN 0716-1018.  http://dx.doi.org/10.4067/s0716-10182018000400413.

Background:

Chikungunya (CHIK) was introduced in The Americas in 2013, spreading rapidly. In 2014, the first imported case was diagnosed in Chile.

Aim:

To identify patients with clinical suspicion of CHIK and describe their clinical and laboratory characteristics.

Patients and Methods:

Patients with suspected CHIK were enrolled. All were confirmed by PCR, IgM or IgG CHIK. A structured survey was applied, which included demographic questions, travel characteristics, clinical manifestations, and laboratory results.

Results:

21 patients were enrolled and CHIK was confirmed in 16, who were further analyzed; 12 were female (75%), average age 39 years (27-52). The Caribbean and South Americawere the most frequent sites of exposure. In 63%, the initial symptom was arthralgia. Most frequent symptoms were myalgias, malaise (both 100%), fever, and polyarthralgia (both 94%). The median duration of arthralgias was 90 days (3-262); in 53% arthralgias lasted ≥ 3 months. Main joints involved were ankles, hands, and wrists; 87% reported invalidating pain. Arthritis lasted longer in men than in women (p < 0.001). 38% of patients presented lymphopenia and one patient mild thrombocytopenia. Two patients required hospitalization, one with severe headaches, the other with acute pyelonephritis.

Conclusions:

Chikungunya should be suspected in returning travelers presenting with fever and severe polyarthralgia. Travelers to endemic areas should apply prevention measures to avoid mosquito bites.

Palabras clave : Chikungunya; Chile; arthropathy; clinical cases; travel medicine; arthralgia.

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