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Revista chilena de infectología

versión impresa ISSN 0716-1018

Resumen

SAMUDIO, Gloria Celeste; MONZON, Ruth; ORTIZ, Lidia María  y  GODOY, Gladys Maribel. Late onset neonatal sepsis in an intensive care neonatal unit: etiological agents and most frequent location. Rev. chil. infectol. [online]. 2018, vol.35, n.5, pp.547-552. ISSN 0716-1018.  http://dx.doi.org/10.4067/s0716-10182018000500547.

Introduction:

Nosocomial neonatal sepsis (NNS) is a frequent entity in intensive care units, causing great morbidity and mortality. The most frequent site is blood, followed by lungs and urine.

Objective:

To know the etiology and most frequent localization of infection in the NNS.

Population, Material and Methods:

Cross sectional study, from January to December 2015, performed in a teaching hospital. All newborns infants were included.

Results:

70 patients were included, 88 episodes of NNS were analyzed. The most frequent localization was bacteremia in 40% of cases, followed by urinary tract infection and VAP in 25% respectively. The bacteria most frequently isolated were staphylococci of different types, followed by multiresistant Acinetobacter. The CNS involvement was 32%. Mortality was 34%, rising up to 50% with a second episode of NNS. The empirical therapy of choice was vancomycin and carbapenem, adjusting to antibiogram.

Conclusions:

The most frequent infection was bacteremia, mainly by staphylococci resistant to methicillin. CNS involvement was elevated, as well as mortality.

Palabras clave : Late onset neonatal sepsis; nosocomial neonatal sepsis; etiology; infection sites.

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