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Revista chilena de infectología

versão impressa ISSN 0716-1018

Resumo

SANTOLAYA, María Elena et al. Antimicrobial therapy in cancer patients and hematopoietic stem cell transplantation receptors. Rev. chil. infectol. [online]. 2019, vol.36, n.2, pp.167-178. ISSN 0716-1018.  http://dx.doi.org/10.4067/S0716-10182019000200167.

This manuscript includes the antiinfective therapeutic resources for immunocompromised patients under chemotherapy by cancer or hematopoietic stem cells transplant (HSCT) receptors. The document presents the antimicrobial therapy indicated in the most prevalent clinical situations in this population and the primary and alternative therapy for some specific microorganisms. The clinical situations included in the analysis are: febrile neutropenia without focus, sepsis, infections of the central nervous system, pneumonia, skin and soft tissue infections, neutropenic enterocolitis and urinary tract infection. The therapeutic resources, recommended doses and special precautions for the use of antimicrobial recommended in bacterial, viral, fungal and parasitic infections in this population are described, including the measurement of plasma concentrations of certain drugs in specific situations.

Palavras-chave : Antimicrobial therapy; cancer; neutropenia; febrile neutropenia; hematopoietic stem cell transplantation.

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