SciELO - Scientific Electronic Library Online

 
vol.37 número4Impacto económico del dengue en ParaguayInfecciones respiratorias virales en episodios de fiebre en niños con trasplante de precursores hematopoyéticos índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

Links relacionados

  • En proceso de indezaciónCitado por Google
  • No hay articulos similaresSimilares en SciELO
  • En proceso de indezaciónSimilares en Google

Compartir


Revista chilena de infectología

versión impresa ISSN 0716-1018

Resumen

LIPARI, Flavio G. et al. Clinical, epidemiological and microbiological characterization of bacteremia produced by carbapenem-resistant enterobacteria in a university hospital in Córdoba, Argentina. Rev. chil. infectol. [online]. 2020, vol.37, n.4, pp.362-370. ISSN 0716-1018.  http://dx.doi.org/10.4067/S0716-10182020000400362.

Background:

Enterobacteriaceae are a major cause of bloodstream infections and their antimicrobial resistance continues to increase. This leads to higher morbidity-mortality rates and public health costs. Carbapenem-resistant Enterobacteriaceae represent a serious challenge globally, since there are few therapeutic options available.

Aim:

Clinical/microbiological characterization of the carbapenem-resistant bacteremia observed over a period of 4 years.

Methods:

Retrospective, observational and descriptive study about bacteremia caused by carbapenem-resistant and susceptible Enterobacteriaceae.

Results:

A total of 84 patients with bacteremia including carbapenem-resistant and susceptible Enterobacteriaceae were analyzed. We found that patients infected with carbapenem-resistant strains presented a higher proportion of: previous antibiotic treatment, hospitalization in intensive care unit (ICU), onset of the bacteremia during hospitalization in ICU and previous infection with extended-spectrum-beta-lactamase producing Enterobacteriaceae. Additionally, we observed a predominance of KPC-producing Klebsiella pneumoniae and an attributable mortality rate of 52.4%.

Discussion:

This study allowed for a better understanding of an emerging problem with high mortality, which in turn is useful for the design and adoption of infection control strategies and effective treatment regimens adapted to our local epidemiology.

Palabras clave : bacteremia; Enterobacteriaceae; Klebsiella pneumoniae; multi drug resistance; carbapenemases; KPC betalactamase.

        · resumen en Español     · texto en Español     · Español ( pdf )