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Biological Research

Print version ISSN 0716-9760

Abstract

EYZAGUIRRE, CARLOS. Chemical and electric transmission in the carotid body chemoreceptor complex . Biol. Res. [online]. 2005, vol.38, n.4, pp.341-345. ISSN 0716-9760.  http://dx.doi.org/10.4067/S0716-97602005000400005.

Carotid body chemoreceptors are complex secondary receptors. There are chemical and electric connections between glomus cells (GC/GC) and between glomus cells and carotid nerve endings (GC/NE). Chemical secretion of glomus cells is accompanied by GC/GC uncoupling. Chemical GC/NE transmission is facilitated by concomitant electric coupling. Chronic hypoxia reduces GC/GC coupling but increases G/NE coupling. Therefore, carotid body chemoreceptors use chemical and electric transmission mechanisms to trigger and change the sensory discharge in the carotid nerve.

Keywords : carotid body; chemosensory activity; glomus cells.

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