Resumen

GUTIERREZ N, MONICA et al. Pulmonary function impairment in patients with idiopathic pulmonary fibrosis. Rev. chil. enferm. respir. [online]. 2008, vol.24, n.4, pp.279-285. ISSN 0717-7348.  http://dx.doi.org/10.4067/S0717-73482008000400002.

Idiopathic pulmonary fíbrosis (LPF) is the most frecuent of idiopathic interstitial pneumonías. The most sensltlve lung function testfor its diagnosis is a low DLCO register. Objective: To analyze LPF's cllnlcal features and to establish its functional disability by DLCO at the time of diagnosis and also to correlate DLCO with 6-minute walked distance test (DR6), saturation pre andpost DR6 and forcea vital capacity (FVC). Methods: We studied retrospective data from 31 patients with LPF, analyzing personal and family history. We also determined pulmonary function parameters: DLCO (stratified in 4 groups: normal, mild, modérate and severe impairment), FVC, DR6 with pre andpost oxygen saturation. Functional impairment according to DLCO was severe in 7patients and modérate in 19 out ofthe 31 patients. Results: An inverse association was observed between DLCO impairment and oxygen saturation levéis in rest, exercise and the difference between them (p < 0.001). Conclusión: Oxygen saturation level in exercise and rest, as well as the difference between them, have a good correlation with DLCO for LPF diagnosis.

Palabras clave : Idiophatic pulmonary fíbrosis; diagnosis; DLCO.

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