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Revista chilena de enfermedades respiratorias

versión On-line ISSN 0717-7348


LOZANO C, JAIME et al. A human metapneumovirus infection in hospitalized infant patients with severe acute respiratory tract infection: A clinical and epidemiological view. Rev. chil. enferm. respir. [online]. 2009, vol.25, n.4, pp.211-217. ISSN 0717-7348.

Human metapneumovirus (hMPV) is a newly recognized virus associated with upper and lower respiratory tract infection (LRTI). A prospective - 2 - years study aimed to evaluate the circulation rate and the clinical features associated with hMPV infection was conducted in children hospitalized by a severe LRTI. Results: hMPV was found in 24 (10.5%) out of the 229 children enrolled. 42%> hMPV patients were under 12 months-old and 58% have at least one risk factor for severe course of the illness. The most common diagnosis was pneumonia (62.5%). Fourty two percent of the patients required assisted ventilation for severe respiratory failure. Co-infections with other respiratory viruses did not result in greater severity of illness. In conclusion our study supports the significant role of hMPV as a major pathogen in severe LRTI in children.

Palabras clave : Respiratory virus; human metapneumovirus; severe lower respiratory tract infection; respiratory failure; mechanical ventilation.

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