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Revista chilena de enfermedades respiratorias

versión On-line ISSN 0717-7348

Resumen

SALDIAS P, FERNANDO; TIRAPEGUI S, FERNANDO  y  DIAZ P, ORLANDO. Mycobacterium avium complex pulmonary disease in immunocompetent adult patients. Rev. chil. enferm. respir. [online]. 2013, vol.29, n.3, pp.162-167. ISSN 0717-7348.  http://dx.doi.org/10.4067/S0717-73482013000300006.

Nontuberculous mycobacteria (NTM) are increasingly recognized as important pulmonary pathogens. Mycobacterium avium intracellulare complex (MAC) causes most lung infections due to NTM. Although the organism was identified in the 1890s, its potential to cause human disease was only recognized 50 years later. Patients with preexisting lung disease or immunodeficiency are at greatest risk for developing MAC infection. The majority of MAC pulmonary cases, however, occur in immunocompetent elderly women in association with nodular infiltrates and bronchiectasis. More recently, pulmonary disease has also been described in immunocompetent patients after exposure to MAC-contaminated hot tubs. We describe two cases of MAC lung disease in immunocompetent adult patients without preexisting lung disease and we review clinical manifestations, diagnostic criteria and treatment of this entity.

Palabras clave : Mycobacterium avium complex; nontuberculous mycobacterium; bronchiectasis; diagnosis; treatment; prognosis.

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