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Revista chilena de enfermedades respiratorias

versión On-line ISSN 0717-7348

Resumen

BRICENO V, CATALINA et al. Difficulties in the selection of a reference equation for the interpretation of the results of DLCO. Rev. chil. enferm. respir. [online]. 2013, vol.29, n.4, pp.191-195. ISSN 0717-7348.  http://dx.doi.org/10.4067/S0717-73482013000400002.

Introduction: In the absence of national reference equations, the ATS recommends comparing the results of the diffusion capacity of healthy subjects in a representative sample of the population with international equations and choosing among them, the one that provides the lowest sum of the residues. Objective: To compare reference equations available in the literature and identify which best meets the selection criteria. Methods: We reviewed 10 reference equations, for each one we calculated the sum of the residues for a sample of 71 healthy subjects and described the characteristics that affect the variability of each one. Results: Since 1985 we have used the single breath method. Only Thompson et al prediction equations 2008 were obtained with instantaneous reading of CO. Equations with the lowest sum of residues (Miller, Roca and Cotes) include smokers and former smokers. Conclusions: We need an equation in non-smokers with methodology that ensures low variability.

Palabras clave : DLCO; lung function; reference equation; reference values.

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