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vol.37 número3DETERMINACIÓN DE ZEARALENONA POR CROMATOGRAFÍA LÍQUIDA DE ALTA RESOLUCIÓN: NORMALIZACIÓN DE UN NUEVO MÉTODO PARA RACIONES ESPECIALES PARA CERDOSEFECTO DE LA DIGESTIÓN EN LA BIODISPONIBILIDAD DE PÉPTIDOS CON ACTIVIDAD BIOLÓGICA índice de autoresíndice de materiabúsqueda de artículos
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Revista chilena de nutrición

versión On-line ISSN 0717-7518

Resumen

PALOMO G, Iván et al. APPLE CONSUMPTION HELPS TO PREVENT CARDIOVASCULAR DISEASES AND CANCER: EPIDEMIOLOGY AND MODE OF ACTION. Rev. chil. nutr. [online]. 2010, vol.37, n.3, pp.377-385. ISSN 0717-7518.  http://dx.doi.org/10.4067/S0717-75182010000300013.

Consumption of fruit and vegetables has the potential to reduce non-transmissible diseases (NTD), such as cardiovascular diseases (CVD) and cancer, which are major public health concerns. Chile is a major apple producer and exporter in the world. Its production is concentrated in the sixth (O’Higgins) and seventh (Maule) regions of Central Chile. Phenolics and flavonoids are responsible for apple's high antioxidant activity. Many epidemiologic studies have shown that a diet rich in apples can reduce cardiovascular events (myocardial infarct and stroke) and some type of cancers. The mechanisms involved are not well understood. Nevertheless, antioxidants are key-players. Some of their in-vitro activities are inhibition of low-density lipoprotein (LDL) oxidation, cholesterol levels reduction, endothelium protection, reduction of neoplastic cells proliferation and apoptosis activation. Consequently, daily apple consumption campaigns in the country should be implemented, as well as funding research focused on molecular mechanisms involved in its antioxidant activity.

Palabras clave : antioxidants; cancer; cardiovascular diseases; phenolics; apple fruit.

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