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Revista chilena de nutrición

versión On-line ISSN 0717-7518

Resumen

SINISTERRA R, Odalis et al. Effectiveness of a precooked maize-based cereal fortified with ferrous gluconate stabilized with glycine or ferrous bisglycinate on iron status of children 24-59 months of age. Rev. chil. nutr. [online]. 2013, vol.40, n.4, pp.369-375. ISSN 0717-7518.  http://dx.doi.org/10.4067/S0717-75182013000400007.

Food fortification is the most effective and sustainable strategy to combat iron deficiency anemia (IDA). The objective of this was to evaluate the effectiveness of a precooked corn-based cereal (Nutricrema®) fortified with ferrous gluconate stabilized with glycine or ferrous bisglycinate chelate on iron status in of preschool children. A prospective, double-blind, cluster-randomized trial was conducted in a rural and indigenous area of Panama. During a six month period, 36 rural community soup-kitchens were divided into two groups randomly assigned to receive either: Group-A: 90 g of cereal with 10 mg of iron as ferrous gluconate stabilized with glycine; or Group-B (n=129): 90 g of cereal with 10 mg of iron as ferrous bisglycinate chelate. A total of 393 children aged 24 to 59 months of both sexes were recruited. Before and after the fortification trial iron status was evaluated. Two hundred and fifty-four children ended the follow-up (125 and 129 in groups A and B, respectively). Prevalence of IDA in group A was 29.6% and 26.4% (NS) before and after the trial, respectively; the corresponding figure for group B was 32.6% and 10.9% (p <0.05), respectively. In conclusion, the precooked corn-based cereal fortified with ferrous bisglycinate is effective in reducing the prevalence of IDA, while the cereal fortified with ferrous gluconate stabilized with glycine did not have a significant effect on the prevalence of IDA.

Palabras clave : preschool children; iron deficiency anemia; fortification; ferrous bisglycinate; ferrous gluconate.

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