SciELO - Scientific Electronic Library Online

 
vol.47 issue3Food environment of a Brazilian public university: challenges to promote healthy eatingRecommendations and effects of dietary fiber for children author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google

Share


Revista chilena de nutrición

On-line version ISSN 0717-7518

Abstract

CAMPELLO LEAL, Claudia et al. Glomerular filtration rate and its relationship with visceral and subcutaneous adiposity: a study with patients from Northeast Brazil. Rev. chil. nutr. [online]. 2020, vol.47, n.3, pp.449-456. ISSN 0717-7518.  http://dx.doi.org/10.4067/S0717-75182020000300449.

Objective:

evaluate the relationship between visceral/subcutaneous adipose tissue (VAT/SAT) and glomerular filtration rate (GFR).

Methods:

A case series study was conducted with 146 male and female adult outpatients at a hospital in Northeast Brazil. VAT and SAT were quantified using computed tomography and GFR was estimated using the formula proposed by the CKD Epidemiology Collaboration. The conceptual model also considered socio-demographic, clinical, anthropometric and lifestyle variables.

Results:

Females accounted for 71.9% of the sample and mean age was 52.5±13.2 years. Mean body mass index indicated obesity in both sexes (men:30.4±5.9 kg/m2; women: 31.6±6.1 kg/m2). For the same mean age and BMI, men had more VAT and a higher VAT/SAT ratio. Mean GFR was similar between sexes and within the normal range. Simple linear regression analysis revealed that 21.8% of the reduction in GFR in males could be explained by the VAT/SAT ratio (p=0.002). Among females, both VAT alone and the VAT/SAT ratio were predictors of GFR reduction (r2=4.8%, p=0.025 and r2=5.3%, p=0.019, respectively).

Conclusion:

Mean VAT and VAT/SAT ratio were compatible with abdominal obesity in both sexes and were related to a reduction in GFR.

Keywords : Abdominal obesity; Glomerular filtration rate; Kidney disease; Visceral fat.

        · abstract in Spanish     · text in English     · English ( pdf )